The San Francisco 49ers (4-5) are heading to the Big Easy to take on the New Orleans Saints (6-2) for their third road game in four weeks.
The Saints are coming off a big win in Week 9, blowing out the Tampa Bay Buccaneers, 38-3. Quarterback Drew Brees showed Tom Brady who owns the NFC South by completing 26-of-32 passes for 222 yards and four touchdowns. The Saints' passing attack was diverse against the Buccaneers, with Brees completing a pass to 12 players.
The 49ers are coming into Week 10 off a brutal loss in the primetime spot during Thursday Night Football against the Green Bay Packers, falling, 34-17. San Francisco will be playing with backups in the secondary, at quarterback, tight end and wide receiver.
This week will be the first game the 49ers have seen fans in the stands. The Mercedes-Benz Superdome will allow 6,000 spectators at Sunday's matchup.
Faithful fans will want to be on the lookout for wide receiver, Richie James. The wide receiver has spent a little more than two years with the 49ers. Last week, James caught nine catches for 184 yards and a touchdown. With Deebo Samuel out this week, the offense will rely on James and rookie receiver Brandon Aiyuk, the McQueen High graduate. The pair will go up against Saints cornerbacks Marshon Lattimore and Janoris Jenkins.
Another offensive player to keep an eye out for is running back Jerick McKinnon. The 49ers will be without Raheem Mostert and Tevin Coleman this week, putting the load on McKinnon and rookie JaMycal Hasty.
Defensively, fans will want to keep their eyes peeled on linebacker, Fred Warner. Warner will be tasked with defending running back Alvin Kamara. Kamara has 471 yards rushing, 565 yards receiving and eight touchdowns. Although Kamara is one of the best running backs in the NFL, Warner ranks 10th in the NFL with 74 tackles. According to Pro Football Focus, Warner while targeted in coverage has a passer-rating-against of just 60.5 – more than 40 points lower than the average linebacker.
On the opposite side of the field, fans will spot a familiar face, linebacker Kwon Alexander. The Saints acquired Alexander from the 49ers in exchange for veteran linebacker Kiko Alonso and a conditional fifth-round draft pick before the trade deadline. Alexander is coming off a high ankle sprain suffered against the the Miami Dolphins in Week 5. If Alexander is healthy and ready to go, the linebacker should start next to Demario Davis.
The over/under for this game is set at 49.5. Oddsmakers believe the Saints will come out on top 30-20.
Following this week’s game, the 49ers have a bye week, giving them time to rest. Next San Francisco will then take on the Rams in Los Angeles. Coming off the bye week t,he 49ers hope to have the following players rejoin the team: Mostert, Coleman, Deebo Samuel and Richard Sherman.